Medical Weight Loss Treatment with Semaglutide and Tirzepatide
Semaglutide and Tirzepatide are two common weight loss injectable treatments revolutionizing medical weight loss. Semaglutide, and Tirzepatide were originally developed to treat type two diabetes and other obesity-related illnesses. Semaglutide was originally marketed under brand names like Ozempic and Wegovy. Tirzepatide was originally marketed as Mounjaro. These innovative, FDA-approved drugs are more than just weight-loss solutions—they represent a shift in our understanding of obesity as a chronic condition that requires targeted, medical intervention.
Target Areas For Treatment
Both Semaglutide and Tirzepatide each have offered a groundbreaking solution in the weight loss world and have gained immense attention, now being administered by providers to assist in all types of weight loss. Meaning, a patient who is not diagnosed with diabetes can be prescribed Semaglutide or Tirzepatide from their provider depending upon their weight loss goals. The byproduct ends up being far more than weight loss, as both Semaglutide and Tirzepatide can also reduce blood pressure, cholesterol, and blood sugar and improve overall health and well-being.
Semaglutide and Tirzepatide both support weight loss by addressing underlying, biological mechanisms that can influence appetite, metabolism, and energy balance. Not only have Semaglutide and Tirzepatide made a tremendous impact on treating obesity, diabetes and other weight related issues. Semaglutide and Tirzepatide have taken away the stigma and shame many face every day surrounding their own weight struggles. Both medications bring a solution to the previous years of struggling individuals of all shapes and sizes may have faced in being their healthiest self.

How does Semaglutide and Tirzepatide work?
Semaglutide is a non-surgical weight loss injectable that is a GLP-1 (Glucagon-like peptide-1, a hormone that helps regulate blood sugar and food intake) medication that activates to help regulate appetite and improve metabolic health. Tirzepatide is a dual incretin receptor agonist, meaning it mimics the actions of both GLP-1 and GIP (Glucose-dependent insulinotropic polypeptide). GIP is a hormone that plays a role in glucose and fat metabolism. This dual action allows Tirzepatide to potentially activate GIP receptors and improve fat metabolism, insulin sensitivity, and energy balance. This additional receptor in Tirzepatide can increase metabolic efficiency to potentially facilitate greater weight loss. Both Semaglutide and Tirzepatide control blood sugar, suppress appetite, and are injected and administered once a week.
Semaglutide and Tirzepatide Treatment Benefits
Semaglutide and Tirzepatide are both FDA-approved medical weight loss treatments that provide an effective solution for achieving significant weight loss and improving overall health, often reducing blood pressure, cholesterol, and regulating blood sugar.
In clinical trials, patients who have been treated with Semaglutide have an average of 15% body weight loss after a year. Patients treated with Tirzepatide have an average of 22% body weight loss after the course of the first year. The GIP activation in Tirzepatide may offer enhanced effects on metabolism, fat breakdown, and energy expenditure, providing broader metabolic benefits compared to Semaglutide.
FAQs
The cost of Semaglutide & Tirzepatide Medical Weight Loss varies depending on the the duration of the treatment plan, an individual’s weight loss goals, dosage and the provider’s recommendations.
The timeline for seeing results for patients being treated for medical weight loss with Semaglutide and Tirzepatide can vary based on factors like dosage, individual response, and adherence to treatment plans. On average, patients typically begin to lose weight within the first 4 weeks of treatment as the medication curbs appetite and slows digestion. Weight loss often accelerates as the dose is gradually increased (titrated), which typically happens every 4 weeks to minimize side effects for both Semaglutide and Tirzepatide. Both treatments for Semaglutide and Tirzepatide often have noticeable results after 12-16 weeks of initial treatment. Peak results typically occur after 6-12 months.
Semaglutide and Tirzepatide are both FDA-approved medical weight loss treatments, considered safe and effective when prescribed and monitored by a qualified healthcare provider.
The most common side effects of Semaglutide and Tirzepatide weight loss injections are typically gastrointestinal (GI) in nature such as nausea, vomiting, diarrhea, constipation and indigestion. These side effects tend to lessen over time as the body adjusts. This is why both weight loss treatments for are titrated slowly and start at low dosages.
Both Semaglutide and Tirzepatide weight loss injections are administered are designed for self-administration or administration by a healthcare provider. These medications are typically delivered through subcutaneous injections (injections under the skin) once weekly. The medication can be safely and painlessly injected in the lower abdomen, thighs, or upper arms.
Depending on your weight loss goals, on average, with Semaglutide, you can expect to lose about 10–15% of your body weight over a year or more. With Tirzepatide, weight loss may reach 22% of your body weight, depending on the dose and duration. Both weight loss results from Semaglutide and Tirzepatide achieve optimal results when combined with healthy diet and exercise. Fillers and collagen biostimulators like Sculptra can also help assist in treating skin laxity and producing collagen for hollow areas caused by weight loss.
Many patients combine their medical weight loss injection treatments with additional body sculpting and fat burning treatments, such as CoolSculpting which leads to permanent fat reduction, and EmSculpt Neo which permanently removes pesky grabbable fat immune to diet and exercise while building muscle tone. Emsculpt is a perfect solution for patients who have lost significant body fat but want to improve their body’s composition by maintaining muscle mass, further toning their body to enhance weight loss results. Other patients may try Kybella. Kybella is specifically designed to target and reduce submental fat (commonly known as a “double chin”) as well as other pinchable problem areas.
“Ozempic face” is the terminology used to refer to a person’s loss of facial volume or sagging skin after significant weight loss from weight loss treatments like Ozempic, Semaglutide and Tirzepetide. Patients looking to prevent or treat “Ozempic face” often pair their weight loss treatment with Dermal fillers. Hyaluronic acid (e.g., Juvederm, Restylane) fillers can replenish lost volume in areas like the cheeks, temples, or under the eyes, giving a more youthful and fuller appearance. Collagen-stimulating injectables (e.g., Sculptra or Radiesse) can help boost collagen production, improving skin elasticity and firmness over time.
Both medications are excellent options for individuals with type 2 diabetes or prediabetes, as they improve blood sugar control while promoting weight loss. Patients who are experiencing challenges in being overweight, and weight-related issues such as hypertension, high blood pressure and high cholesterol are also good candidate. Semaglutide can also effectively treat sleep apnea.
Patients considering medical weight loss injections such as Semaglutide and Tirzepatide should first and foremost schedule an appointment with one of our expert providers to discuss their goals, health issues, and treatment plan options. Patients should expect to have a check-in with their provider every week for the first month and follow the recommended dosages. Patients should also understand that weight loss with these medications is gradual and sustainable, typically averaging 1–2 pounds per week after the initial adjustment period.

Discovery Medical Weight Loss Treatments
At Supriya Aesthetic Dermatology, we believe everyone deserves to feel and look their best and have extensive experience in seeing tremendous results from both Semaglutide and Tirzepatide. Schedule a consultation with one of our qualified healthcare experts and Supriya Aesthetic Dermatology to discuss your weight loss options today!