Renuva® Fat Regeneration

Natural, Long-Lasting Volume Restoration

Renuva® is an FDA-cleared, non-surgical treatment that restores lost facial and body volume by stimulating your body to grow its own new, living fat. This innovative injectable uses a microscopic “scaffold” to trigger natural fat regeneration in the face, hands, and body. It is the ideal solution for patients seeking a biocompatible, long-term alternative to synthetic fillers, resulting in rejuvenation that looks, feels, and moves exactly like your natural anatomy.

What is Renuva?

While traditional dermal fillers are composed of synthetic gels, Renuva is a purified adipose (fat) matrix. It is a bio-inductive injectable derived from processed tissue that has been cleared of donor cells, leaving behind only the essential biological “architecture” found in healthy human fat.

How does Renuva work?

Renuva is an injectable treatment that works like a guide for your body to rebuild its own natural volume. It contains the same supportive elements found in your own fat, so once it is placed, your body gradually replaces Renuva with new, healthy fat cells over the following months. As these cells form and new blood vessels grow, the area gently fills and looks naturally fuller, smoother and more youthful. Renuva matrix gradually becomes your body’s own tissue over 3–6 months, creating volume that looks and feels natural.

How long do the results from Renuva last?

Unlike transient hyaluronic acid (HA) fillers that require frequent maintenance every 6–12 months, Renuva provides a semi-permanent solution for volume restoration.

Once the initial regeneration phase is complete (typically around the 6-month mark), the newly formed volume is biologically stable living tissue. Therefore, the longevity of your results does not depend on the product “wearing off,” but rather mimics the natural lifespan of your own fat cells. While individual metabolic factors vary, clinical data indicates that these results can persist for up to 10 years.

Your Renuva Treatment Journey

What to Expect

Renuva is a minimally invasive, in-office procedure performed by our expert providers. The treatment is designed for maximum comfort and requires no general anesthesia or surgical incisions.

The Procedure

The treatment typically takes 30 to 60 minutes. Your provider will use a fine needle or cannula to precisely place the Renuva matrix into the target areas. Most patients report only mild pressure or a slight pinching sensation.

Immediate Recovery

There is minimal downtime. You may experience slight redness, swelling, or minor bruising at the injection site, which typically resolves within a few days. We recommend avoiding strenuous exercise or high-heat environments (like saunas) for 24–48 hours post-treatment.

The Integration Phase

Unlike instant fillers, Renuva works with your biology. Over the first few weeks, the initial volume from the injection will settle as your body begins the cellular recruitment process to populate the matrix.

Final Results

Optimal results appear gradually over 3 to 6 months. During this window, your body completes the transition of the matrix into your own living fat cells. The result is a smooth, natural contour that persists for years.

Expert Tip: Because Renuva relies on your body’s natural regenerative capabilities, maintaining a stable weight and staying hydrated can help support the health of your newly formed fat cells.

Who Is a Good Candidate for Renuva?

Renuva is a versatile solution for men and women seeking natural volume restoration without the complexity of surgery. You may be an ideal candidate if you fall into the following categories:
  • Age-Related Volume Loss: Those experiencing hollow temples, sunken cheeks, or “bony” appearances on the hands and décolletage.
  • Medical Weight Loss Support: Patients dealing with “Ozempic Face” or rapid facial volume depletion after significant weight loss.
  • Liposuction or Surgical Irregularities: Individuals seeking to smooth out divots, contour irregularities, or depressed scars.
  • Low Body Fat (The “Off-the-Shelf” Alternative): Unlike traditional fat grafting, Renuva requires no donor site. This makes it the perfect choice for thin patients who do not have enough harvestable body fat for surgery.

Is Renuva right for you?

While Renuva is highly biocompatible, it may not be suitable for individuals who are pregnant or breastfeeding, those with active infections at the injection site, or patients with a history of severe anaphylactic allergies. Renuva should only be injected into areas where natural fat already exists; therefore, it is not used for lip augmentation or direct muscle injections.

What makes Renuva unique?

Renuva can be used unlike other regenerative injectables and fillers because it’s fat regeneration, this means it’s soft, supple and replaces like for like by plumping up your skin and thickness lost with aging. We consider Renuva unique for its fat regeneration particularly in the neck as well as facial volume loss. With the new trend of medical weight loss, combined with aging, many men and women alike are suffering from hollow face volume loss and skin that appears additionally crepey without significant fat loss and aging.

Why Choose Supriya Aesthetic Dermatology for Renuva?

At Supriya Aesthetic Dermatology, we specialize in the intersection of restorative medicine and aesthetic excellence. Led by Dr. Supriya Tomar, our team leverages over 60 years of combined clinical expertise to provide the most advanced regenerative skincare innovations available today.

  • Expertise in Regenerative Aesthetics: We are leaders in bio-inductive treatments like Renuva, focusing on “like-for-like” tissue restoration rather than temporary synthetic masking.
  • Evidence-Based Results: Our approach is rooted in medical science. We prioritize treatments that are clinically proven to promote neovascularization and natural skin health.
  • Customized Treatment Architecture: No two faces age the same way. Dr. Tomar and her team specialize in layering therapies—combining Renuva with Sculptra or neurotoxins—to create a structural foundation tailored to your unique anatomy.
  • Safety & Precision: By utilizing advanced injection techniques, we ensure that Renuva is placed precisely within the subcutaneous layer for optimal fat cell recruitment and seamless integration.

Frequently Asked Questions

Renuva is used for volume loss, while Botox will assist with the appearance of wrinkles. Botox cannot provide the same effect of a filler or regenerative aesthetics for volume and is exclusively to reduce the appearance of wrinkles. Botox, Dysport, Daxxify and Xeomin are injectable neurotoxins that relaxes targeted muscles to soften wrinkles and prevent new lines from forming. Meaning, restoring volume (Renuva) often is paired with a treatment like Botox to help assist to smooth out fine lines and wrinkles.

Yes, Renuva can be paired well with HA fillers such as Juvéderm, RHA, and Restylane. Renuva builds slow, natural fat-based volume over months, this handles the deeper, long-lasting regenerative volume, while HA fillers add instant contour, quick and precise shaping, lift or definition on top of the foundation of Renuva. Used together, they can create a more complete and balanced result.

Yes, Renuva and Sculptra complement each other because they regenerate different types of natural volume. Sculptra is typically injected for deeper collagen to support the tissue, while Renuva is utilized to regenerate soft supple volume. Renuva helps your body rebuild fat, while Sculptra stimulates collagen and restore the skin. When used together, they create a more structured, longer-lasting result.

Renuva can soften the look of cellulite by filling and rounding out deep skin divots. As the product is replaced with your body’s own regenerated fat, the surface becomes smoother and more even, reducing the appearance of cellulite over time.

Renuva can soften the look of cellulite by filling and rounding out deep skin divots. As the product is replaced with your body’s own regenerated fat, the surface becomes smoother and more even, reducing the appearance of cellulite over time.

Schedule Your Renuva® Consultation Today

Take the first step toward natural, long-lasting rejuvenation. At Supriya Aesthetic Dermatology, we specialize in advanced regenerative treatments that are as unique as you are. Whether you are looking to restore facial volume, address “Ozempic face” hollows, or smooth body contours, our expert team is here to guide your transformation.
Visit us at our West Palm Beach or Jupiter offices to learn how the power of fat regeneration can help you achieve a youthful, refreshed appearance.